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Alachua County Health Department

Perinatal Hepatitis B - Alachua County Health Department

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Perinatal Hepatitis B Prevention Program

In 1992, the state of Florida passed a regulation requiring the testing of all pregnant women for the hepatitis B virus. Today, the Perinatal Hepatitis B Prevention Program is mandated by Florida Administrative Code 64D-3013(6). The purpose of this program is to identify pregnant women who test positive for the hepatitis B virus and coordinate or provide treatment for their infants to prevent the transmission of the virus. The Advisory Committee on Immunization Practices (ACIP) has made the following recommendations regarding the testing for HBsAg and anti-HBs and vaccination of infants born to HBsAg mothers:

  1. Infants born to women who are HBsAg-positive will receive Hepatitis B Immune Globulin (HBIG) and three doses of hepatitis B vaccine.
  2. The HBIG and first dose of hepatitis B vaccine should be given within 12 hours of birth, as long as the infant is physiologically stable.
  3. Infants will be tested for HBsAg and anti-HBs 3 to 9 months after completing the hepatitis B series to determine the success of therapy.
  4. Successful immunization results in a positive anti-HBs and negative HBsAg.
Infants who are negative for anti-HBs and HBsAg can follow one of the two following options:
  1. Give a fourth dose of hepatitis B vaccine and retest in one month. If the test is still negative, give the fifth and sixth doses of hepatitis B vaccine based on the recommended schedule and retest HBsAg and anti-HBs one month after the completion of the second series of shots.
  2. Give a complete second series of hepatitis B vaccines and retest one month after completion.

(Specific authority 381.0011(6), (13), 381.0013(2), 381.006, 384.25(2), 384.33 FS. Law Implemented 381.0011(4), (6), (8), 381.003(1), 381.0031, 384.25(2), 384.27 FS. History-New 12-29-77, Amended 6-14-78, 6-7-82, 11-6-85, Formerly 10D-3.91, Amended 7-5-87, 7-19-89, 2-26-92, 10-20-93, 11-1-94, 7-21-96, Formerly 10D-3.091, Amended 7-5-99, 6-4-00.)

Without the administration of the Hepatitis B Immunoglobulin (HBIG) and hepatitis B vaccines, 90% of infected infants will become chronic hepatitis B carriers. These children are then infectious to others, and at high risk for developing serious liver disease, cirrhosis or primary liver cancer.

In Alachua County, the Perinatal Hepatitis B Prevention Program Coordinator is Isabel Anasco, RN, BSN. When a pregnant woman tests HBsAg-positive, the perinatal hepatitis B coordinator sends an alert to the hospital or birth center where the woman plans to deliver. The coordinator works with the hospital or birth center to assure the infant receives the HBIG and first hepatitis B vaccine. She also coordinates the follow-up care and vaccinations of the infants with the health department or private provider. The coordinator must update all information regarding the care and follow-up of the mother and infant to the statewide perinatal hepatitis B registry.

All hepatitis B vaccines and follow-up testing for the infant are free of charge at the Alachua County Health Department. No appointment is necessary to obtain the hepatitis B vaccines or the testing; however, it is advisable to call in advance to expedite the services.

Contact Information

   Contact    Number
   Isabel Anasco, RN, BSN    (352) 334-7981 or (352) 334-8842
   Fax    (352) 334-7935

Please do not hesitate to contact us with any questions or concerns.

Alachua County Health Department | 224 SE 24th Street | Gainesville, FL 32641 | (352) 334-7900
This page was last modified on: 03/4/2010 11:50:36