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PrEP (Pre-Exposure Prophylaxis)

Is a comprehensive HIV prevention strategy that involves the daily use of antiretroviral medications to reduce the risk of HIV infection in HIV-negative individuals.  In July 2012, the US Food and Drug Administration approved the use of Truvada (TDF/FTC) for use as PrEP in HIV prevention in sexually active HIV–negative individuals.  PrEP should be used in conjunction with other prevention methods to reduce the risk of infection.
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PrEP Resources:
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CDC PrEP Fact Sheet

Truvada for PrEP Fact Sheet

PrEP Webinar (HIV Prevention Program, HIV/AIDS and Hepatitis Section, FL DOH)


AIDSinfo- PrEP

PEP (Post Exposure Prophylaxis)

Post Exposure Prophylaxis (PEP) involves taking antiretroviral medications as soon as possible after a potential exposure to HIV to reduce the likelihood of HIV infection. There are two types of PEP: 1) occupational PEP, or an exposure that happens in the workplace (such as a needle stick in a healthcare setting), and 2) non-occupational PEP (nPEP), or when someone is potentially exposed to HIV through sexual intercourse or injection drug use.

To be effective, PEP must begin with 72 hours of exposure and consists of 2-3 antiretroviral medications that must be taken for 28 days. A physician must determine what treatment is appropriate based on the nature of the exposure. Starting PEP after a potential exposure does not guarantee that someone exposed to HIV will not become infected.

PEP Resources:
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July 2013 Updated Guidelines for HIV Prophylaxis Following Non-Occupational Exposure (nPEP)

AETC- PEP Information

CDC- Antiretroviral Treatment for Prevention of HIV Transmission PEP Resources

Non-Occupational PEP Guidelines

Occupational PEP Guidelines

OSHA Fact Sheet- Bloodborne Pathogen Exposure Incidents

For information regarding medication assistance