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The Florida Department of Health works to protect, promote & improve the health of all people in Florida through integrated state, county, & community efforts.

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E. coli O157:H7 and Hemolytic Uremic Syndrome (HUS)

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Hemolytic Uremic Syndrome (HUS) is a reportable medical condition in the State of Florida. Clinical characteristics of Hemolytic Uremic Syndrome (HUS) include hemolytic anemia, renal injury, and low platelet count. HUS primarily occurs following a gastrointestinal illness and is most commonly associated with shiga-like toxin-producing Escherichia coli (STEC), including Escherichia coli 0157:H7.   In addition, HUS may be related to other types of bacteria, viruses and fungi.

Hemolytic Uremic Syndrome primarily affects children < 5 years of age and elderly persons. The red blood cells are destroyed and the kidneys fail. According to the Centers for Disease Control and Prevention, approximately 2%-7% of E. coli O157:H7 infections lead to HUS.