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PEP, or Post-Exposure Prophylaxis, is an HIV-prevention strategy using anti-retroviral medications to prevent acquiring HIV following a possible exposure. If you think you’ve been exposed to HIV and are in need of PEP, please DO NOT email the Florida Department of Health, Division of Disease Control, HIV/AIDS Section as these are administrative offices. Please contact your local hospital emergency room, urgent care clinic, or local county health department for PEP evaluation and treatment. You may also find local PEP providers using this link (Provider Locator Map). To be effective, PEP must begin within 72 hours of exposure and consists of 2–3 antiretroviral medications that must be taken for 28 days. A physician must determine what treatment is appropriate based on the nature of the exposure. Starting PEP after a potential exposure does not guarantee that someone exposed to HIV will not acquire HIV; however, the sooner you begin PEP, the better. Every hour counts.
PrEP (Pre-Exposure Prophylaxis)
PrEP is a comprehensive HIV prevention strategy that involves the daily use of antiretroviral medications to reduce the risk of HIV infection in HIV-negative individuals. PrEP should be used in conjunction with other prevention methods to reduce the risk of sexually transmitted infection.
Visit our PrEP Locator to find a PrEP or nPEP provider in Florida.
Ready, Set, PrEP
General Info and Enrollment
Ready, Set, PrEP is a new nationwide program led by the U.S. Department of Health and Human Services (HHS). The Ready, Set, PrEP program provides PrEP medications at no cost to individuals who qualify. Check eligibility requirements and enroll in the program at getyourprep.com. Health care providers can also use this site to enroll a patient.
Factsheets, posters, info cards, and social media content (Facebook, Twitter, and Instagram graphics) available for download to use and help spread the word about the benefits of PrEP medications and how to access the Ready, Set, PrEP program. Factsheets are available for consumers, health care professionals, and Indian Health Service. Content included in this toolkit may be customized and tailored to your needs. Questions about materials can be directed to ReadySetPrEP@hhs.gov.
Content included in this toolkit may be customized and tailored to your needs. Questions about materials can be directed to ReadySetPrEP@hhs.gov.
PrEP Provider Resources
FloridaHealth PrEP provider toolkits, resource guides, posters and brochures are available upon request. Email DiseaseControl@flhealth.gov for info.
- AETC Guidelines for PrEP and PEP
- CDC Clinical Practice and Provider Guidelines
- NASTAD Patient Assistance and Co-Payment Assistance Fact Sheet
- PrEP Clinical Trials - CDC
General Audience Resources
PEP (Post Exposure Prophylaxis)
PEP involves taking antiretroviral medications as soon as possible after a potential exposure to HIV to reduce the likelihood of HIV infection. There are two types of PEP: 1) occupational PEP, for an exposure that happens in the workplace (such as a needle stick in a healthcare setting), and 2) non-occupational PEP (nPEP), for when someone is potentially exposed to HIV through sexual intercourse or injection drug use.
*To be effective, PEP must begin with 72 hours of exposure and consists of 2-3 antiretroviral medications that must be taken for 28 days. A physician must determine what treatment is appropriate based on the nature of the exposure. Starting PEP after a potential exposure does not guarantee that someone exposed to HIV will not become infected.
PEP Provider Resources
- Updated Guidelines for Antiretroviral Post-Exposure Prophylaxis After Sexual, Injection Drug Use, or Other Non-Occupational Exposure to HIV
- OSHA Fact Sheet