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Signs and Symptoms

Contact the Bureau of Chronic Disease Prevention

What are the signs and symptoms of lupus?

Lupus symptoms vary from one person to another. Among some people, symptoms come and go. Different symptoms may also appear at different times over the course of the disease. The most common signs and symptoms of lupus include:

  • Butterfly-shaped rash across cheeks and nose
  • Extreme fatigue
  • Headaches
  • Painful or swollen joints
  • Fever
  • Anemia
  • Swelling (edema) in feet, legs, hands and/or around eyes
  • Chest pain during deep breathing
  • Sun or light sensitivity
  • Hair loss
  • Abnormal blood clotting

Many of these symptoms mimic those of other connective tissue diseases, such as rheumatoid arthritis, scleroderma, and sjögren’s syndrome.

For more information, please visit the Lupus Foundation of America at